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KMID : 0385520050180060491
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Analytical Science & Technology
2005 Volume.18 No. 6 p.491 ~ p.494
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Potentiometric performances of polymer membrane electrode based on cyclosporin
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Rhee IS
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Abstract
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The main component governing selectivity in ion-selective electrodes and optodes is the ionophore. For this reason, a member of natural products that possess selective ion-binding properties have long been sought after. By applying this principle, the performance of cyclosporin used as neutral carriers for calcium selective polymeric membrane electrode was investigated. The calcium ion-selective electrode based on cyclosporin gave a good Nernstian response of 26.6 ㎷ per decade for calcium ion in the activity range 1×10^(-6) M to 1×10-² M. The optimized calcium ion-selective electrode displayed very comparable selectivity for Ca²+ ion against alkali and alkaline earth metal ions, Na+, and Mg²+ in particular.
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